Anyway, the results are as follows. Normal values and details in parentheses.
Tests from March 24
CD4, synthroid (25 mg)
TSH - 3.24 (0.3-4.7)
T4 Free - 14.0 (9.1-23.8)
T3 Free - 4.3 (2.5-5.7)
LH Serum - 1.3 (follicular = 2.4-6.6) **LOW**
FSH Serum - 4.4 (follicular = 3.0-22.0)
Testosterone 1.9 (adult female = 0.3-4.0)
Estradiol - 181 (follicular = 0-921)
Prolactin 7.6 (3.3-26.7)
Tests from March 25
CD5, synthroid (25 mg), 12-hr fasting (unless indicated)
Insulin Fasting - 180 (40-190)
Insulin 2 hour - 1290 (120-1240) **HIGH**
Glucose Tolerance Fasting - 5.0 normal (3.6-6.0 normal; 6.1-6.9 impaired; >6.9 possible diabetes mellitus)
Glucose Tolerance 2 hour - 7.7 normal (3.6-7.7 normal; 7.8-11.0 impaired; >11.0 possible diabetes mellitus)
APTT - 34 (26-37)
INR - 1.0 (0.9-1.3)
Homocysteine - 9 (5-15)
Anti dsDNA - 5.0 (0-19.9 negative)
Antinuclear AB (ANA) - 1:40 **POSITIVE**; Titre - 1:40, Pattern - homogeneous, speckled
Anti-Thyroid peroxidase - negative
Anti-Thyroglobulin - negative
Lupus anticoagulant - negative
Russell Viper Venom - negative
Protein S Free - 1.04 (>0.40)
Protein C Function - 1.35 (0.75-1.60)
Act. Prot. C Resist. Ratio - 2.8 (2.3-3.6)
Here is what I draw from these results:
- The high insulin resistance is PCOS. Even the fasting levels are high in the normal range, so to me, it's rather obvious. I expect that this will require Metformin again, likely at 1500 mg/day, whereas all my previous doc would prescribe was 500 mg/day. NOT enough. This might help us in quite significant way.
- The Positive antinuclear AB (ANA) test indicates autoimmune disease. With the other tests, lupus and a variety of other things are ruled out. I think it hearkens back to the thyroid and it might even indicate Hashimoto's Disease. I expect that the RE will want to increase my dosage of synthroid, likely up to 50 mg/day.
- My TSH is still over 3.0. Again, I was told that they wanted to see it at 1.0 to get and maintain a pregnancy. So... yeah, synthroid (see above).
- LH levels are way low. Thank heavens for Clomid and injections; that ought to correct that problem.
- At least my FSH levels are good. That's nice to know.